Irf1 CLIA Kit for Mouse(Mus musculus) | EIAab.comIrf1 CLIA Kit for Mouse(Mus musculus)

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Index > Protein center > Irf1(Gene name) > Mouse

Irf1 (Gene name),

Interferon regulatory factor 1 (Protein name ), IRF1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Irf1;

Protein name:

Interferon regulatory factor 1(IRF-1);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

329

Sequence:

50:

100:

150:

200:

250:

300:

329:

NMDSIMWMDS | LLGNSVRLPP | SIQAIPCAP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00605

KEGG:

mmu:16362

UniGene:

Mm.105218

SMR:

P15314

String:

P15314

Uniprot:

P15314

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ELISA Kit for Mouse IRF-1

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E1564r

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ELISA Kit for Mouse IRF-1

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E1564m

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MSDS:

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96T

ELISA Kit for Mouse IRF-1

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E1564b

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96T

ELISA Kit for Mouse IRF-1

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E1564c

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MSDS:

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96T

ELISA Kit for Mouse IRF-1

Cat.:

E1564h

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ELISA Kit for Mouse IRF-1

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E1564p

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MSDS:

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96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564m

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MSDS:

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96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564h

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MSDS:

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96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564c

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MSDS:

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96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564b

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MSDS:

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96T

CLIA Kit for Mouse IRF-1

Cat.:

U1564r

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96T

Polyclonal Antibody for Mouse IRF-1

Cat.:

P1564Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse IRF-1

Cat.:

P1564Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse IRF-1

Cat.:

P1564Rb-r

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40ug/0.2ml

Monoclonal Antibody for Mouse IRF-1

Protein for Mouse IRF-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements."
Miyamoto M. , Fujita T. , Kimura Y. , Maruyama M. , Harada H. , Sudo Y. , Miyata T. , Taniguchi T.
Cell54:903-913(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary gland.
3.

"Degradation of transcription factor IRF-1 by the ubiquitin-proteasome pathway. The C-terminal region governs the protein stability."
Nakagawa K. , Yokosawa H.
Eur. J. Biochem.267:1680-1686(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
4.

"IRF family of transcription factors as regulators of host defense."
Taniguchi T. , Ogasawara K. , Takaoka A. , Tanaka N.
Annu. Rev. Immunol.19:623-655(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
5.

"PIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1."
Nakagawa K. , Yokosawa H.
FEBS Lett.530:204-208(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIAS3;SUMOYLATION;FUNCTION
6.

"Activities of IRF-1."
Kroeger A. , Koester M. , Schroeder K. , Hauser H. , Mueller P.P.
J. Interferon Cytokine Res.22:5-14(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
7.

"IRF-1 as a negative regulator of cell proliferation."
Romeo G. , Fiorucci G. , Chiantore M.V. , Percario Z.A. , Vannucchi S. , Affabris E.
J. Interferon Cytokine Res.22:39-47(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
8.

"IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors."
Honda K. , Taniguchi T.
Nat. Rev. Immunol.6:644-658(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
9.

"Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program."
Negishi H. , Fujita Y. , Yanai H. , Sakaguchi S. , Ouyang X. , Shinohara M. , Takayanagi H. , Ohba Y. , Taniguchi T. , Honda K.
Proc. Natl. Acad. Sci. U.S.A.103:15136-15141(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH MYD88
10.

"Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1."
Kim E.-J. , Park J.-S. , Um S.-J.
Biochem. Biophys. Res. Commun.377:952-956(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION;FUNCTION
11.

"IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression."
Fragale A. , Gabriele L. , Stellacci E. , Borghi P. , Perrotti E. , Ilari R. , Lanciotti A. , Remoli A.L. , Venditti M. , Belardelli F. , Battistini A.
J. Immunol.181:1673-1682(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Regulation of immunity and oncogenesis by the IRF transcription factor family."
Savitsky D. , Tamura T. , Yanai H. , Taniguchi T.
Cancer Immunol. Immunother.59:489-510(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
13.

"IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction."
Stirnweiss A. , Ksienzyk A. , Klages K. , Rand U. , Grashoff M. , Hauser H. , Kroeger A.
J. Immunol.184:5179-5185(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
14.

"Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection."
Brien J.D. , Daffis S. , Lazear H.M. , Cho H. , Suthar M.S. , Gale M. Jr. , Diamond M.S.
PLoS Pathog.7:E1002230-E1002230(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"Structure of IRF-1 with bound DNA reveals determinants of interferon regulation."
Escalante C.R. , Yie J. , Thanos D. , Aggarwal A.K.
Nature391:103-106(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 7-111

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